Voltammetric study of antioxidant activity of the extract Thymus crebrifolius Klok.

Authors

DOI:

10.15328/cb2026_79

Keywords:

Thymus crebrifolius Klok., antioxidant activity, ascorbic acid, ultrasound-assisted extraction, voltammetry

Abstract

Oxidative processes in the body are one of the main mechanisms of oxidative stress syndrome. Active oxygen species play a decisive role in the development of free radical pathologies, which are accompanied by lipid peroxidation, mutagenic changes in proteins and cellular metabolism disorders. It is of interest to study the antioxidant activity of the dry extract of Thymus crebrifolius Klok. in comparison with ascorbic acid using the voltammetry method.

It was shown that the extract of Thymus crebrifolius Klok. exhibited an antioxidant activity coefficient equal to 1,36 ± 0,06, calculated on the basis of the change in the reduction current compared to the control solution. The study used a 40% aqueous-alcoholic solution of the extract of Thymus crebrifolius obtained by ultrasonic extraction. Extraction was carried out from the upper part of the plant (leaves, young shoots, flowers) at room temperature, 40 kHz twice for 30 minutes. The obtained data indicate the presence of pronounced antioxidant activity in the thyme extract, which is confirmed by its electrochemical reaction to reduction. However, compared to ascorbic acid, the activity was lower, which is probably due to a lower concentration of phenolic compounds or a more complex matrix of the extract.

Author Biographies

  • A.M. Akhmetalimova, Karaganda State Industrial University

    PhD, senior lecturer at the Department of Chemical Technology and Ecology

  • S.K. Kabieva, Karaganda State Industrial University

    professor, candidate of chemical sciences, head of the Department of Chemical Technology and Ecology 

  • G.N. Musina, Abylkas Saginov Karaganda Technical University

    candidate of chemical sciences, Associate Professor of the Department of Chemistry and Chemical Technologies 

  • G.A. Erkinova, Karaganda State Industrial University

    teacher of the Department of Chemical Technology and Ecology

  • R.K. Zhaslan, Karaganda State Industrial University

    PhD, Associate Professor of the Department of Chemical Technology and Ecology

  • D.K. Kuandykov, Karaganda State Industrial University

    senior lecturer of the Department of Chemical Technology and Ecology

  • E.V. Sitdikova, Karaganda State Industrial University

    senior teacher of the Department of Chemical Technology and Ecology

  • F.B. Khamkhoeva, Karaganda State Industrial University

    master’s student of the Department of Chemical Technology and Ecology 

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Published

2026-06-30

How to Cite

Voltammetric study of antioxidant activity of the extract Thymus crebrifolius Klok. (2026). Chemical Bulletin of Kazakh National University, 119(2), In Press. https://doi.org/10.15328/cb2026_79

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